ifn-γ promotes apoptosis of melanocytes in vitiligo

نویسندگان

zohreh jadali skin and stem cell research center, tehran university of medical sciences, tehran, iran; school of public health, tehran university of medical sciences, tehran, iran; skin and stem cell research center, tehran university of medical sciences, tehran, iran. tel: +98-2122215558, fax: +98-2122674977

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Increased expression of the cytokine interferon (IFN)-γ plays a pivotal role in vitiligo-induced depigmentation. However, the major source of IFN-γ in vitiligo patients and the mechanisms underlying melanocyte destruction are unknown. In this study, a large number of skin infiltrating IFN-γ+ cells and CD8+ T cells were detected in progressive vitiligo. Among the peripheral blood mononuclear cel...

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عنوان ژورنال:
journal of skin and stem cell

جلد ۲، شماره ۴، صفحات ۰-۰

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